MMRI Research priorities

The exceptional character of the studies conducted by Mossakowski Medical Research Institute Polish Academy of Sciences results from its unique departmental structure combining basic research with clinical practice. The research area focuses on key experimental medicine problems, solvable at the level of basic body functions and pathologies. However, numerous research programs concentrate on clinical problems and a great number of investigated issues exceed medical practice being therefore analysed by means of experimental models.

The Institute's research priorities include the following research directions:

1. Molecular mechanisms of Central Nervous System development  and pathologies. Disease modeling and personalized medicine using animal models,  human iPSC and brain organoids.

2. Cancer - basic research. Development of a "multi-onko-map" - multiomic map of molecular programs in the most lethal cancers and diagnostics of brain tumors (neurogenetics and neuropathology).

3. Healthy aging and longevity. Research on long-lived people (including centenarians), prevention of obesity and diabetes, rehabilitation in age-related diseases.

4. Rare diseases. Basic research and diagnostics (neuromuscular and neurodegenerative diseases)

5. Translational research in regenerative medicine. Preclinical studies on animal models and experimental therapy of CNS disorders using human stem cells isolated from different tissues and organs, e.g. bone marrow and adipose tissue.

6. Experimental pharmacology. Designing new drugs. Pharmacological neuroprotection.

Scientific disciplines practised at the Institute: Medical sciences