Deadline for applications: 31.10.2025
Expected starting date: November/December 2025
Procedure ID: ZKTS.110.1.2025

Project description
The project focuses on the purinergic P2X7 receptor (P2X7R) as a key molecular mediator of metabolic dysfunction and neuronal degeneration in Parkinson’s disease (PD). Accumulating evidence shows that α-synuclein (α-Syn) directly interacts with P2X7R, triggering calcium overload, oxidative stress, mitochondrial failure, and impaired glucose metabolism. Using a combination of in vivo PD models (α-Syn oligomer injection, behavioral testing, MRI) and in vitro studies (primary neuronal cultures, molecular and imaging techniques), we will dissect the role of P2X7R in:
• oxidative stress and redox homeostasis,
• mitochondrial quality control (mitophagy, mtUPR),
• central carbon metabolism,
• structural and behavioral changes in the PD brain.
The results are expected to uncover novel mechanisms of α-Syn neurotoxicity and establish P2X7R as a potential therapeutic target in PD.

Key responsibilities
• Planning and conducting in vivo and in vitro experiments (animal work, stereotactic surgery, behavioral tests, cell culture, transfection).
• Application of molecular biology and biochemical techniques (immunohistochemistry, confocal microscopy, mitochondrial isolation, Western blotting, PCR, enzymatic assays).
• Analysis and interpretation of results, preparation of manuscripts, and presentation of findings at national and international conferences.

Candidate requirements
• Ph.D. in neurobiology, neuropharmacology, molecular biology, or related field (within 7 years before start of employment).
• Proven experience in animal experimentation (valid ethical approval required) and cell culture techniques.
• Strong publication record (JCR-indexed journals) and conference activity.
• Fluent communication and writing in English.
• Knowledge of biochemical and molecular methods; ability to perform statistical analyses.
• Motivation for scientific work, independence, good organizational skills, and the ability to work in a team.

Additional assets: experience with neurodegenerative disease models, mitochondrial biology, or international research mobility.
Additional benefits: private health insurance, Multisport card, support for conference participation
Application
Applicants should send the following documents to This email address is being protected from spambots. You need JavaScript enabled to view it. 
• CV with full publication list,
• motivation letter including research interests,
• copy of Ph.D. diploma,
• contact details of at least one academic referee.

Apply via email to This email address is being protected from spambots. You need JavaScript enabled to view it. Please use the subject line: Application – Postdoc Position Neurobiology.
In the email title, please include: „ Scholarship grantee/Student” and procedure ID: ZKTS.110.1.2025

Procedure ID: ZKTS.110.1.2025
Deadline for applications: 31.10.2025
Expected starting date: November/December 2025
Duration: 36 months (with possible extension for an additional 12 months; first 6 months’ probation)
Salary: 8500 PLN gross/month + performance-based bonuses

We reserve the right to invite only selected candidates for interviews.

INFORMATION CLAUSE ON PERSONAL DATA PROCESSING
Pursuant to Article 13 of the Regulation (EU) 2016/679 of the European Parliament and of the Council of 27 April 2016 on the protection of natural persons with regard to the processing of personal data and on the free movement of such data, and repealing Directive 95/46/EC (General Data Protection Regulation), Mossakowski Medical Research Institute, Polish Academy of Sciences hereby informs:
- The Controller of your personal data is the Mossakowski Medical Research Institute, Polish Academy of Sciences, A. Pawińskiego 5 St., 02-106 Warsaw, Poland (“MMRI PAS”)
- The Controller has designated the Data Protection Officer who can be contacted via the following e-mail address: This email address is being protected from spambots. You need JavaScript enabled to view it. or the post address of Controller.
- Your personal data will be processed for the purpose of carrying out a recruitment process and selecting an employee and concluding a contract for employment at the MMRI PAS.
- MMRI PAS processes Your personal data in relation to a legal obligation (the Article 6.1.c of the GDPR) pursuant to Article 221 § 1 of the Act of 26 June 1974 Labour Code or Your consent understood by sending them to MMRI PAS (the Article 6.1.a of the GDPR) for data not listed on Labour Code, and their application does not affect the possibility of participating in the recruitment / competition. If you do not want us to process additional data, please do not include it in the documents.
- By submitting your candidacy, you consent to the fact that if you win the recruitment / competition, your name and surname together with information about the recommendation for employment will be posted on the MMRI PAS website.
- Your application with personal data will be processed for period necessary for realization of purposes indicated in p. 3 - for a maximum of one month and then your application with personal data will be deleted.
- With regard to processing of Your personal data for purposes mentioned in p. 3, Your personal data might by shared with following recipients or categories of recipients: entities supporting MMRI PAS in its business processes, in particular administrative and economic service and authorized entities.
- Within the limits and on the terms set out in the GDPR, you have the right to request access to your personal data, rectification, deletion or limitation of processing, as well as the right to submit a declaration of withdrawal of consent to the processing of personal data at any time. Withdrawal of consent does not affect the lawfulness of the processing which was carried out on the basis of consent before its withdrawal, as well as the processing of data processed by the administrator on the basis of other provisions.
- You have the right to lodge a complaint to the President of the Office for the Protection of Personal Data (Stawki 2 St., 00-193 Warszawa).

Job Vacancy is announced
by the Director of Mossakowski Medical Research Institute, Polish Academy of Sciences in Warsaw

for the position of
assistant
in the Translational Platform for Regenerative Medicine

City: Warsaw
Position: assistant
Scientific discipline: medical sciences
Announcement date: September 22nd, 2025
Application deadline: October 6th, 2025
Expected date of competition results announcement: the second half of October 2025
Date of taking the position: November 2025
Link to page: Translational Platform for Regenerative Medicine
Keywords: assistant, mesenchymal stem cells, organotypic slice culture, flow cytometry.

The current research program of the Translational Platform for Regenerative Medicine.
In TPRM we conduct research on stem cells and their application in the treatment of neurodegenerative diseases. Our work focuses on analyzing MSC–NSC interactions in the stem cell niche, developing 3D cultures (spheroids, biomimetic scaffolds), isolating MSC subpopulations with high regenerative potential, and studying extracellular vesicles (EVs) as carriers of biological information. We work with in vitro, ex vivo, and in vivo models, using advanced molecular and cellular biology methods. Our goal is to develop new strategies to support nervous system regeneration. We offer attractive opportunities for professional growth for young researchers, PhD students, and specialists interested in stem cell biology, biomaterials, and translational medicine.

The area of the research in which the candidate would participate:
• basic research on mesenchymal stem/stromal cells (MSC) and neural stem cells (NSC);
• evaluation of the therapeutic potential of MSCs, NSCs, and extracellular vesicles derived from them.

Description of job position activities:
• conducting scientific research on cell cultures and organotypic slice cultures;
• implementing new research technologies to improve the quality of scientific studies;
• actively publishing scientific research results;
• preparing research projects to obtain funding;
• active participation in Laboratory seminars;
• representing the Laboratory at national and international scientific conferences.

Requirements for the position of assistant:
• master’s degree (or equivalent) in medical sciences, biological sciences, or related fields;
• minimum of 3 years’ experience working with human MSC and/or human NSC cultures;
• knowledge of techniques: isolation and culture of MSCs from Wharton’s jelly, culture of human NSCs and human vascular endothelial cells; flow cytometry, organotypic hippocampal slice culture, confocal microscopy, and basic molecular biology methods (RNA isolation, real-time PCR, Luminex);
• experience in carrying out research projects;
• documented active participation in national and international conferences and symposia;
• ability to design, organize, and conduct scientific research as well as formulate research hypotheses;
• independence and good work organization;
• ability to work in a team;
• fluent English;
• indicating the Mossakowski Medical Research Institute, Polish Academy of Sciences (MMRI PAS), as a first place of employment.

Additional requirements (preferred):
• knowledge of techniques for isolation and analysis of extracellular vesicles;
• original scientific publications, where the candidate is the first or co-first author.

We offer:
• full-time work contract;
• scientific development;
• attendance in conferences and internships;
• additional financial support from the social fund;
• chance of joining group life insurance, co-financing of a medical package, and co-financing of a Multisport card;
• friendly work environment.

Required documents:
• cover letter with information about scientific interests;
• CV containing information on education, scientific achievements, publications and previous jobs;
• a list of publications;
• a copy of the diploma confirming the possession of the required professional title or academic degree;
• documents confirming the fulfillment of other requirements specified in the announcement of the competition for the position of assistant.

How to apply:
The application should be addressed to the Director of MMRI PAS. The required documents in electronic form
(pdf format only) should be sent to the following e-mail address: This email address is being protected from spambots. You need JavaScript enabled to view it. and must be received by the Institute by October 6th, 2025.

Please include the following job offer identification number in your application: SDI.111.7.2025.
The date of receipt of documents by MMRI PAS is decisive - the applications received after the deadline will not be considered.
Anticipated result announcement date: the second half of October 2025.
Envisaged job starting date: November, 2025.
The competition is carried out following "Regulations of the employment for the scientific positions in MMRI PAS".

INFORMATION CLAUSE ON PERSONAL DATA PROCESSING

Under Article 13 of Regulation (EU) 2016/679 of the European Parliament and of the Council of 27 April 2016 on the protection of natural persons concerning the processing of personal data and on the free movement of such data, and repealing Directive 95/46/EC (General Data Protection Regulation), Mossakowski Medical Research Institute, Polish Academy of Sciences hereby informs:
 The Controller of your data is the Mossakowski Medical Research Institute, Polish Academy of Sciences, A. Pawińskiego 5 St., 02-106 Warsaw, Poland (“MMRI PAS”)
 The Controller has designated the Data Protection Officer who can be contacted via the following e-mail address: This email address is being protected from spambots. You need JavaScript enabled to view it. or the postal address of the Controller.
 Your data will be processed to carry out a recruitment process and select an employee and conclude a contract for employment at the MMRI PAS.
 MMRI PAS processes Your data concerning a legal obligation (Article 6.1.c of the GDPR) according to Article 221 § 1 of the Act of 26 June 1974 Labour Code or Your consent understood by sending them to MMRI PAS (Article 6.1.a of the GDPR) for data not listed on Labour Code, and their application does not affect the possibility of participating in the recruitment/competition. If you do not want us to process additional data, please do not include it in the documents.
 By submitting your candidacy, you consent to the fact that if you win the recruitment/competition, your name and surname together with information about the recommendation for employment will be posted on the MMRI PAS website.
 Your application with personal data will be processed for the period necessary for the realization of purposes indicated in p. 3 - for a maximum of one month and then your application with personal data will be deleted.
 Concerning processing of Your data for purposes mentioned in p. 3, Your data might be shared with the following recipients or categories of recipients: entities supporting MMRI PAS in its business processes, in particular administrative and economic service and authorized entities.
 Within the limits and on the terms set out in the GDPR, you have the right to request access to your data, rectification, deletion, or limitation of processing, as well as the right to submit a declaration of withdrawal of consent to the processing of personal data at any time. Withdrawal of consent does not affect the lawfulness of the processing which was carried out based on consent before its withdrawal, as well as the processing of data processed by the administrator based on other provisions.
 You have the right to lodge a complaint to the President of the Office for the Protection of Personal Data (ul. Stawki 2, 00-193 Warszawa).

Job Vacancy is announced

by the Director of Mossakowski Medical Research Institute, Polish Academy of Sciences in Warsaw

for the position of

assistant

in the Department of Stem Cell Bioengineering

City: Warsaw
Position: assistant
Scientific discipline: medical sciences
Announcement date: September 19th, 2025
Application deadline: October 3rd , 2025
Expected date of competition results announcement: the second half of October 2025
Date of taking the position: November, 2025
Link to page: Department of Stem Cell Bioengineering
Keywords: assistant, neural stem cells, aging, modeling neurodegenerative diseases, human brain organoids.

The current research program of the Department of Stem Cell Bioengineering:
Research conducted at the Department of Stem Cell Bioengineering concerns the development and pathology of the CNS and the use of stem cells for modeling diseases and CNS therapy, the role of aging in development
of neurodegenerative diseases.

The area of the research in which the candidate would participate:
• participation in basic, preclinical and translational research in the field of stem cells and brain organoids;
• study of molecular mechanisms of development and pathology of the central nervous system using human induced pluripotent stem cells;
• development and standardization of gene delivery systems into iPSC lines;
• implementation of life imaging methods for tracking developmental pathways in 3D cellular structure;
• modelling of aging and neurodegenerative diseases with human brain organoids.

Description of job position activities:
• planning and conducting research related to the use of stem cells and brain organoids in modeling of aging and neurodegeneration;
• performing the necessary biochemical, molecular and electrophysiological studies;
• investigating transcriptomic and epigenetic changes at the single-cell level using advanced techniques single-cell RNA sequencing (scRNA-seq) and single-cell ATAC-seq (scATAC-seq);
• derivation of reporter cell lines using gene editing technology;
• active participation in the Polish and foreign scientific conferences;
• preparing publications for world recognized scientific journals;
• obtaining external funding for research projects: writing individual grant projects and in consortia;
• active participation in the scientific and educational life (providing support for trainees) of the Department and the Institute;
• activity for the dissemination of science.

Requirements for the position of assistant:
• having a master’s degree (or equivalent) in the field of medical, biological, or related sciences;
• experience in laboratory work including induced pluripotent stem cells culture;
• experience in derivation and culture of human neural stem cell population;
• experience in molecular biology methods (DNA, RNA isolation, RT-qPCR, NGS) and cell biology (ELISA);
• experience in immunohistochemical techniques and fluorescence microscopy imaging;
• documented active participation in conferences and scientific internships;
• independence and good organization of work;
• creativity, ability to work individually and in a team;
• fluency in English, both spoken and written;
• indication Mossakowski Medical Research Institute Polish Academy of Sciences (MMRI PAS) as a first place of employment.

Additional requirements (desirable):
• experience in somatic cells reprograming (fibroblasts) and development of induced pluripotent stem cell clonal cultures;
• experience in derivation of reporter cell lines;
• experience in derivation of human mid-brain organoid;
• knowledge of modern omics research techniques (ATAC-seq, ChIP-seq, scRNAseq) and genome editing methods;
• ability to analyze data and knowledge of statistical methods used in scientific research, ability to use software for statistical data analysis (e.g., GraphPad Prism, SPSS, R, Statistica);
• documented participation in the research projects for which funding was independently obtained through competitions.

We offer:
• employment contract (full-time);
• opportunity for scientific development and independence in project management for which funding was obtained independently by the candidate;
• participation in the implementation of other projects;
• attendance in conferences and internships;
• additional financial support from the social fund;
• opportunity to join a group insurance program, medical service package, and to obtain a Multisport card
on preferential terms;
• friendly work environment.

Required documents:
• cover letter with information about scientific interests;
• curriculum vitae containing information on education, scientific achievements, and previous jobs;
• list of publications;
• copy of the diploma confirming the possession of the required professional title or academic degree;
• documents confirming the fulfillment of other requirements specified in the announcement of the competition for the position of assistant.

How to apply:
The application should be addressed to the Director of MMRI PAS. The required documents in electronic form
(pdf format only) should be sent to the following e-mail address: This email address is being protected from spambots. You need JavaScript enabled to view it. and must be received by the Institute by October 3rd, 2025.

Please include the following job offer identification number in your application: SDI.111.6.2025.
The date of receipt of documents by MMRI PAS is decisive - the applications received after the deadline will not be considered.
Anticipated result announcement date: the second half of October 2025
Envisaged job starting date: November, 2025.
The competition is carried out following "Regulations of the employment for the scientific positions in MMRI PAS".

INFORMATION CLAUSE ON PERSONAL DATA PROCESSING
Under Article 13 of Regulation (EU) 2016/679 of the European Parliament and of the Council of 27 April 2016 on the protection of natural persons concerning the processing of personal data and on the free movement of such data, and repealing Directive 95/46/EC (General Data Protection Regulation), Mossakowski Medical Research Institute, Polish Academy of Sciences hereby informs:
 The Controller of your data is the Mossakowski Medical Research Institute, Polish Academy of Sciences, A. Pawińskiego 5 St., 02-106 Warsaw, Poland (“MMRI PAS”)
 The Controller has designated the Data Protection Officer who can be contacted via the following e-mail address: This email address is being protected from spambots. You need JavaScript enabled to view it. or the postal address of the Controller.
 Your data will be processed to carry out a recruitment process and select an employee and conclude a contract for employment at the MMRI PAS.
 MMRI PAS processes Your data concerning a legal obligation (Article 6.1.c of the GDPR) according to Article 221 § 1 of the Act of 26 June 1974 Labour Code or Your consent understood by sending them to MMRI PAS (Article 6.1.a of the GDPR) for data not listed on Labour Code, and their application does not affect the possibility of participating in the recruitment/competition. If you do not want us to process additional data, please do not include it in the documents.
 By submitting your candidacy, you consent to the fact that if you win the recruitment/competition, your name and surname together with information about the recommendation for employment will be posted on the MMRI PAS website.
 Your application with personal data will be processed for the period necessary for the realization of purposes indicated in p. 3 - for a maximum of one month and then your application with personal data will be deleted.
 Concerning processing of Your data for purposes mentioned in p. 3, Your data might be shared with the following recipients or categories of recipients: entities supporting MMRI PAS in its business processes, in particular administrative and economic service and authorized entities.
 Within the limits and on the terms set out in the GDPR, you have the right to request access to your data, rectification, deletion, or limitation of processing, as well as the right to submit a declaration of withdrawal of consent to the processing of personal data at any time. Withdrawal of consent does not affect the lawfulness of the processing which was carried out based on consent before its withdrawal, as well as the processing of data processed by the administrator based on other provisions.
 You have the right to lodge a complaint to the President of the Office for the Protection of Personal Data (ul. Stawki 2, 00-193 Warszawa).