Assistant (f/m/x) R1
City: Warsaw
Position: Assistant (f/m/x)
Scientific discipline: medical sciences
Announcement date: October 30th, 2026
Application deadline: November 15th, 2026
Expected date of competition results announcement: December 2026
Date of taking the position: January 2027
Link to page: Department of Neurogenetics and Functional Genomics
The current research program of the Department of Neurogenetics and Functional Genomics:
• functional studies of the underlying mechanisms of familial Alzheimer’s disease, with a particular focus on synaptic dysfunction, using a model based on reprogrammed human neurons and brain organoids;
• identification and comprehensive characterization (including bioinformatics) of mutations and genomic variants associated with the clinical phenotype of CUN neurodegenerative diseases, muscular, neurodevelopmental, neuropsychiatric, and related disorders;
• analysis of cellular and molecular processes (including mitochondrial function and mitophagy) underlying frontotemporal dementia (FTD) spectrum disorders caused by mutations in the PGRN, MAPT, and C9orf72 genes;
• development of new cellular models using iPSC lines derived from patients with Alzheimer’s disease (AD) caused by presenilin (PSEN1/2) mutations;
The area of the research in which the candidate would participate:
• in vitro functional studies of early pathological molecular hallmarks of Alzheimer’s disease using an organoid model and reprogrammed neurons derived from patients with familial type presenilin gene mutations, as well as with sporadic type;
• multi-omic studies of the early stages of Alzheimer's disease;
• participation in the development of a platform providing access to brain organoid models from patients with neurodegenerative diseases, for the purpose of testing research hypotheses with translational potential.
Description of job position activities:
• conducting cell culture experiments (human neurons, 2D) and organoid culture experiments (brain organoids, 3D);
• developing / establishing neuronal or brain organoid models from new patients (recruited continuously in the laboratory) strating from primary fibroblasts culture via appropriate reprogramming stages
• conducting functional studies of synaptic and epigenetic markers in vitro models;
• assisting with electrophysiological recordings (patch-clamp in whole-cell configuration) and analysis using microelectrode array (MEA) technology, as well as calcium response recordings (GCAMP8, Fura2-AM);
• active participation in the scientific and organizational activities of the Department and the Institute;
• initiative and commitment to solving experimental tasks, analyzing, interpreting, and discussing results;
• preparing publications based on the obtained results;
• representing the Department and the Institute at scientific conferences.
Requirements:
• a master’s degree (or equivalent) in biological or medical sciences;
• authoring or co-authoring of scientific publications;
• proficiency in cell biology techniques (in vitro cell culture), molecular biology, and confocal microscopy;
• good knowledge of bioinformatics methods and statistical data analysis;
• independence and excellent work organization;
• creativity, ability to work in a team;
• designating the MMRI PAS as the primary place of employment
• good or very good command of English;
• communicative command of Polish.
Additional requirements (desirable):
• experience with organoid culture methods;
• knowledge of electrophysiological measurement methods;
We offer:
• employment at one of the leading scientific institutions in Poland;
• employment contract (full-time position);
• opportunity for scientific development and independence in project management for which funding was obtained independently by the candidate;
• participation in the implementation of other projects;
• opportunity to attend conferences and to participate in internships abroad;
• additional support from the social fund (i.e. support in difficult life situations, childcare subsidies and low interest loans);
• possibility to join Employee Capital Plans (PPK);
• additional benefits such as opportunity to join a group life insurance program, medical service package, and a Multisport card on preferential terms;
• work in a good team, in a nice atmosphere;
• friendly work environment.
Required documents:
• cover letter with information about scientific interests;
• curriculum vitae containing information on education, scientific achievements, and previous jobs;
• list of publications;
• a copy of the diploma confirming the possession of the required professional title or academic degree;
• documents confirming the fulfillment of other requirements specified in the announcement of the competition.
How to apply:
The application should be addressed to the Director of Mossakowski Medical Research Institute, Polish Academy of Sciences. The required documents in electronic form (pdf format only) should be sent to the following e-mail address: This email address is being protected from spambots. You need JavaScript enabled to view it. and must be received by the Institute by November 15th, 2026.
Please include the following job offer identification number in your application: SDI.111.13.2026.
The date of receipt of documents by MMRI PAS is decisive - the applications received after the deadline will not be considered.
Anticipated result announcement date: December 2026
Envisaged job starting date: January 2027
The competition is carried out following Employment Rules and Regulations for the position of the Researcher in MMRI PAS. Regulation_on_employment_in_scientific_positions_czerwiec_2026_EN.pdf
INFORMATION CLAUSE ON PERSONAL DATA PROCESSING
According to Article 13 of Regulation (EU) 2016/679 of the European Parliament and of the Council of 27 April 2016 on the protection of natural persons concerning the processing of personal data and the free movement of such data, and repealing Directive 95/46/EC (General Data Protection Regulation), Mossakowski Medical Research Institute, Polish Academy of Sciences hereby informs:
1. The Controller of your data is the Mossakowski Medical Research Institute, Polish Academy of Sciences, A. Pawińskiego 5 St., 02-106 Warsaw, Poland ("MMRI PAS")
2. The Controller has designated the Data Protection Officer who can be contacted via the following e-mail address: This email address is being protected from spambots. You need JavaScript enabled to view it. or the postal address of the Controller.
3. Your data will be processed to carry out a recruitment process and select an employee and conclude a contract for employment at the MMRI PAS.
4. MMRI PAS processes Your data concerning a legal obligation (Article 6.1.c of the GDPR) according to Article 221 § 1 of the Act of 26 June 1974 Labour Code or Your consent understood by sending them to MMRI PAS (Article 6.1.a of the GDPR) for data not listed on Labour Code, and their application does not affect the possibility of participating in the recruitment/competition. If you do not want us to process additional data, please do not include it in the documents.
5. By submitting your candidacy, you consent to the fact that if you win the recruitment/competition, your name and surname together with information about the recommendation for employment will be posted on the MMRI PAS website.
6. Your application with personal data will be processed for the period necessary for the realization of purposes indicated in p. 3 - for a maximum of one month and then your application with personal data will be deleted.
7. Concerning the processing of Your data for purposes mentioned in p. 3, Your data might be shared with the following recipients or categories of recipients: entities supporting MMRI PAS in its business processes, in particular administrative and economic service and authorized entities.
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9. You have the right to lodge a complaint to the President of the Office for the Protection of Personal Data (ul. Stanisława Moniuszki 1A, 00-014 Warszawa).


